Organic nitroso compounds
Cayman Chemical N-Nitroso Nebivolol, Purity: ≥95% (mixture of isomers), CAS: 1391051-68-5, 10 mg
A derivative of nebivolol
World Precision Instrument SNAP S-Nitroso-N-acetyl-D-penicillamine-SNAP25
SNAP is a stable green crystalline S-nitrosothiol compound that mimics the action of nitric oxide in vivo. It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors. Call for details. M.W. 220.2, Purity > 98% by NMR or TLC.
World Precision Instrument SNAP S-Nitroso-N-acetyl-D-penicillamine-SNAP50
SNAP is a stable green crystalline S-nitrosothiol compound that mimics the action of nitric oxide in vivo. It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors. Call for details. M.W. 220.2, Purity > 98% by NMR or TLC.
Cayman Chemical N-Nitroso-N-ethylaniline, Purity: ≥98%, CAS: 612-64-6, 25 mg
An N-nitrosamine; non-carcinogenic in a survival assay using 2FR450 Rauscher leukemia virus-infected rat embryo cultures; a synthetic intermediate in the synthesis of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as CXCR2 antagonists
Cayman Chemical N-Nitroso Sarcosine, Purity: ≥95%, CAS: 13256-22-9, 50 mg
A carcinogen; induces the formation of metastatic liver carcinomas in mice at 225 mg/kg
Cayman Chemical N-Nitroso-N-methylaniline, Purity: ≥98%, CAS: 614-00-6, 100 mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Medchemexpress LLC L-tryptophanamide, N-((3-methyl-1H-inden-2-yl)carbonyl)-D-alanyl-N-((1S)-2-((2R)-2-methyl-2-oxiranyl | 1416709-79-9 | 98.9% | 618.72 g·mol⁻¹ | C37H38N4O5 | 10MM 1ML
PR-924 is a selective tripeptide epoxyketone inhibitor of the immunoproteasome subunit LMP-7, intended for research use in biochemical and cellular assays. It is supplied in ready-to-use solutions and in solid quantities to support formulation and dosing studies.
- Selective tripeptide epoxyketone LMP-7 inhibitor.
- Available as 10 mM solution in DMSO and multiple solid sizes.
- High reported purity: 98.9%.
- Molecular weight 618.72 g·mol⁻¹; formula C37H38N4O5.
- Soluble in DMSO; in vivo formulation options described for PEG300/tween/saline and corn oil.
- Storage recommendations provided for powder and in solvent to preserve stability.
Medchemexpress LLC Tripeptide epoxyketone immunoproteasome (LMP-7) inhibitor | 1416709-79-9 | 98.9% | 618.72 g/mol | C37H38N4O5 | 50MG
A selective tripeptide epoxyketone inhibitor of the immunoproteasome LMP7 subunit for biochemical and cellular research. It covalently modifies proteasomal N-terminal threonine active sites and has demonstrated antitumor activity in preclinical studies.
- Selective LMP7 (β5i) immunoproteasome inhibitor.
- Covalently modifies N-terminal threonine active sites.
- Reported IC50 of 22 nM against LMP7.
- Demonstrated inhibition of multiple myeloma cell growth and induction of apoptosis.
- High chemical purity (98.9%).
- Enantiomeric excess 100%.
- Molecular weight 618.72 g/mol and formula C37H38N4O5.
- Supplied in small research pack sizes, e.g., 50 mg.
- For research use only; not for human use.
Chemscene ChemScene | N-Nitroso-N-phenylhydroxylamine aluminum salt | 500G | CS-0201281 | 0.98 | 15305-07-4| MFCD00144989 | 438.33
ChemScene | N-Nitroso-N-phenylhydroxylamine aluminum salt | 500G | CS-0201281 | 0.98 | 15305-07-4| MFCD00144989 | 438.33
Enzo Life Sciences Spermine NONOate (5mg). CAS: 136587-13-8
Nitric oxide (NO) donor. A convenient reagent for preparing aqueous solutions of NO. Alternative name: SPER/NO, (Z)-1-N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino-diazen-1-ium-1,2-diolate. Purity: ≥97% (NMR). Solubility: Soluble in water, methanol or 100% ethanol. Long Term Storage: -80°C.
Enzo Life Sciences Spermine NONOate (25mg). CAS: 136587-13-8
Nitric oxide (NO) donor. A convenient reagent for preparing aqueous solutions of NO. Alternative name: SPER/NO, (Z)-1-N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino-diazen-1-ium-1,2-diolate. Purity: ≥97% (NMR). Appearance: White to off-white crystalline solid. Solubility: Soluble in water, methanol or 100% ethanol. Long Term Storage: -80°C.
Medchemexpress LLC N-Nitrosomorpholine | 59-89-2 | 99.98% | 5 G
N-Nitrosomorpholine is a photosensitive nitrosamine that is carcinogenic and can be used to construct animal cancer models. It is for research use only and not sold to patients.
- Photosensitive nitrosamine
- Carcinogenic agent
- Used to construct animal cancer models
- For research use only
- Not sold to patients
Medchemexpress LLC N-Nitrosomorpholine | 59-89-2 | 99.9% | 1 G
N-Nitrosomorpholine is a photosensitive nitrosamine known for its carcinogenic properties, primarily used in research to construct animal cancer models. It is intended for research applications only and not for patient use.
- Carcinogenic agent for research purposes.
- Used to construct animal cancer models.
- Induces liver disease, including cytoplasmic and nuclear changes.
- Causes toxic damage, single-cell necrosis, and loss of glycogen.
- Promotes giant cell production, bile duct proliferation, and fibrosis.
- Leads to cirrhosis and metastatic liver cancer in animal models.
- Supports the study of molecular and histological changes, including increased serum glutamate-oxaloacetate aminotransferase levels and liver damage.